目的 基于CiteSpace软件的可视化分析扩张型心肌病领域的研究热点和趋势。方法 以
CNKI（中国知网）及Web of Science收录的2005~2020年扩张型心肌病研究相关文献为研究对象，采用
CiteSpace进行文献计量学分析。结果 最终纳入中文文献763篇、英文文献2900篇；CNKI中发文的前三
的作者为王振涛、廖玉华、李为民，Web of Science发文前三的作者为GIANFRANCO SINAGRA、MARCO
MERLO、GIULIA BARBATI；CNKI发文最多的研究机构为四川大学华西医院心内科，Web of Science发
文最多的研究机构为斯坦福大学；Web of Science发文最多的国家为美国，中心性最高的为美国；CNKI
高频关键词有“扩张型心肌病”、“心肌病”、“心力衰竭”等，Web of Science高频关键词有“dilated
cardiomyopathy”、“heart failure”、“cardiomyopathy”等；较大的关键词聚类CNKI有7个，Web of
Science有6个；CNKI得到9个突显词，Web of Science得到12个突显词。结论 扩张型心肌病研究领域在临
床方向的中心，早期为扩张型心肌病所致心力衰竭的治疗和超声心动图的应用，中期为扩张型心肌病的
新型疗法，其中中医药疗法备受关注，近期为心脏磁共振钆延迟增强显像；在基础方向的中心，早期为
扩张型心肌病的基因因素和自身免疫机制，近期为扩张型心肌病的氧化应激机制、心肌纤维化机制及相
关基因。但不同研究人员及研究机构之间合作较少，建议增强研究人员及研究机构间的交流合作并开展
高质量的临床研究，以期为扩张型心肌病的临床防治奠定基础。

Objective To conduct a visual analysis of the research hotspots and trends in dilated cardiomyopathy based on CiteSpace software. Method Based on CiteSpace software, a bibliometric analysis of the relevant literature on dilated cardiomyopathy from 2005 to 2020 included in CNKI and Web of Science. Results Finally, 763 Chinese documents and 2900 English documents were included in the present study. Results showed that the first three authors of CNKI's articles are Wang Zhentao, Liao Yuhua, and Li Weimin, and the first three authors of Web of Science articles are GIANFRANCO SINAGRA, MARCO MERLO, GIULIA BARBATI. The research institution with the most CNKI publications is the Department of Cardiology, West China Hospital, Sichuan University, and the research institution with the most publications on the Web of Science is Stanford University. The country with the most published Web of Science articles and the country with the highest centrality is the United States. The results showed that "dilated cardiomyopathy," "cardiomyopathy" and "heart failure" were the keywords with the highest intensity. Visual analysis results show seven large keyword clusters for CNKI and 6 for Web of Science. Nine prominent words are generated in CNKI, and 12 prominent words are generated in Web of Science. Conclusion The clinical research on dilated cardiomyopathy began to focus on the treatment of dilated cardiomyopathy with heart failure or arrhythmia. Then the diagnosis and risk assessment of dilated cardiomyopathy became the center. After that, new drugs and therapies for dilated cardiomyopathy became the research center, and Chinese medicine therapy became a favored direction. In the direction of basic research, the genetic factors and autoimmune factors of dilated cardiomyopathy were centered in the early stage, and then the focus shifted to the myocardial fibrosis mechanism of dilated cardiomyopathy. However, there is little cooperation between different researchers and research institutions. It is recommended to strengthen the communication and cooperation between researchers and research institutions and carry out high-quality clinical research to lay the foundation for the clinical prevention and treatment of dilated cardiomyopathy.

国家自然科学基金(81973836);北京市中医药科技
发展资金项目(JJ-2020-69);首都卫生发展科研专项重点攻关项目
(2020-1-4151);中国中医科学院中医药科技重大成果引导项目(ZZ13-
ZD-04)